Study finds cabernet sauvignon dry red wine ameliorates atherosclerosis in mice by regulating inflammation and endothelial function, activating AMPK phosphorylation, modulating gut microbiota, decreasing lesion size

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May 4, 2023 (press release) –

A study from ScienceDirect suggests that the antioxidant polyphenols in red wine may help prevent cardiovascular diseases. Using a mouse model of atherosclerosis, the research found that oral administration of Cabernet Sauvignon dry red wine reduced atherosclerotic lesion size, alleviated hyperlipidemia, improved liver lipid accumulation, and promoted lipid metabolism. The wine increased the relative abundance of various beneficial gut microorganisms and contained polyphenols that may have mediated the preventative effects by reducing inflammation and regulating other bodily processes.

Industry Intelligence editor's note: Information originally published in ScienceDirect's Food Research International. To view the full article, please visit

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