Cellino Biotech completes Series A financing of US$80M, led by Bayer's investment arm; company aims to develop autonomous end-to-end manufacturing of stem cell-based therapies, expand patient access to treatments

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CAMBRIDGE, Massachusetts and LEVERKUSEN, Germany , January 25, 2022 (press release) –

  • Cellino aims to significantly expand patient access to stem cell-based therapies with autonomous end-to-end manufacturing / Proceeds will expand machine learning, software, and hardware capabilities and to develop early-stage Good Manufacturing Practice (GMP) capabilities to support clinical trials, with plans to build the first autonomous human cell foundry in 2025 / Investment further strengthens existing company portfolio of Leaps by Bayer in the fields of cell and gene therapies

Cellino Biotech, Inc., an autonomous cell therapy manufacturing company, today announced the completion of a Series A financing of $80 million, led by the impact investment arm of Bayer AG – Leaps by Bayer – 8VC, and Humboldt Fund. New investors in the round include Felicis Ventures and others, joining existing investors The Engine and Khosla Ventures. The company has raised a total of $96 million in gross proceeds from private financings to date.

Cellino is on a mission to make stem cell-based regenerative medicines accessible for all eligible patients. Stem cell-derived therapies are poised to prevent, treat, and potentially reverse diseases for which no options are available today or the current standard of care is insufficient. Currently, large scale production of stem cell therapies is challenging due to extensive manual handling, high variability, and expensive manufacturing costs.

Cellino’s next-generation manufacturing platform combines artificial intelligence (AI) and laser technology to automate cell therapy manufacturing to reduce expenditures and overcome scaling limitations. The groundbreaking approach has the potential to reduce production costs by an order of magnitude and expand patient access to cell therapies. Investing in Cellino represents a unique opportunity for Leaps by Bayer to continue to fund the development of next-generation therapies.

“Leaps by Bayer’s mission is to invest in paradigm-shifting technologies that provide long-term answers to some of today’s biggest challenges,” said Juergen Eckhardt, MD, Head of Leaps by Bayer. “We believe that artificial intelligence-driven manufacturing is the next important inflection point towards industrializing cell therapies, which undoubtedly are one of the core technologies to advance biotech from treatment to prevention or disease reversal. Cellino’s truly transformative approach to autonomously manufacture stem cell-based therapies fits precisely with our ambition to regenerate lost tissue function for millions of patients.”

“Cellino’s software-driven closed loop platform is necessary to industrialize stem cell-derived therapies, which are highly complex in nature,” said Nabiha Saklayen, Ph.D., CEO & Co-Founder, Cellino. “We are grateful for the support of new and existing investors who are committed to building an AI-driven future for regenerative medicine. I am honored to lead and grow a team of industry experts across laser physics, deep learning, and stem cell biology who are on a mission to democratize cell therapies for all eligible patients.”

Proceeds from the Series A financing will considerably expand Cellino’s software, machine learning, and hardware capabilities for end-to-end manufacturing of both autologous and allogeneic stem cell-based therapies. In addition, Cellino is building a long-term collaboration with the National Institutes of Health (NIH), where senior investigator Dr. Kapil Bharti is leading the first autologous induced pluripotent stem cell (iPSC)-derived clinical trial in the US, to validate Cellino’s manufacturing approach. The company also plans to build early-stage GMP capabilities to support clinical trials.

Cellino’s next-generation process combines label-free imaging, high-speed laser editing, and artificial intelligence (AI) to automate cell reprogramming, expansion, and differentiation in a closed cassette format. Cellino’s approach enables the parallel processing of thousands of patient samples in a single facility, which is vital for scalable manufacturing. Inspired by the semiconductor industry, the company plans to build the first autonomous human cell foundry in 2025.

About Bayer and Leaps by Bayer
Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Its products and services are designed to help people and planet thrive by supporting efforts to master the major challenges presented by a growing and aging global population. Bayer is committed to drive sustainable development and generate a positive impact with its businesses. At the same time, the Group aims to increase its earning power and create value through innovation and growth. The Bayer brand stands for trust, reliability and quality throughout the world. In fiscal 2020, the Group employed around 100,000 people and had sales of 41.4 billion euros. R&D expenses before special items amounted to 4.9 billion euros. For more information, go to www.bayer.com.

Leaps by Bayer, a unit of Bayer AG, leads impact investments into solutions to some of today’s biggest challenges in health and agriculture. The investment portfolio includes more than 50 companies. They are all working on potentially breakthrough technologies to overcome some specific challenges such as providing sustainable organ & tissue replacement, reducing the environmental impact of agriculture, preventing, or curing cancer, and others. For more information, go to leaps.bayer.com.

About Cellino
Cellino is an autonomous, closed loop cell therapy manufacturing company. The company is on a mission to democratize stem cell-based therapies for all eligible patients. Cellino is based in Cambridge, MA. For additional information, please visit www.cellinobio.com. Follow us on Twitter @cellinobio.

For more information, go to leaps.bayer.com
Follow us on Twitter: @LeapsByBayer

Forward-Looking Statements
This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments.

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