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AstraZeneca’s injectable Evusheld COVID-19 antibody ineffective against omicron GA.4.6 warns FDA; AstraZeneca reports BA4.6 accounts for 6.2% of infections globally while dominant BA.5 subvariant accounts for 85% of current infections

Japan joins US, EU in approving AstraZeneca’s injectable asthma drug Tezspire tezepelumab, developed with Amgen; Tezspire treats severe, refractory bronchial asthma that can't be controlled with inhaled corticosteroids, long-term maintenance therapies

AstraZeneca to end work on experimental cholesterol drug ION449 under development with partner Ionis; the two firms still working together on kidney drug ION532, fatty liver disease drugs ION839 and ION455, cancer therapy ION736

AstraZeneca’s long-acting injectable COVID-19 antibody therapy Evusheld tixagevimab and cilgavimab receives approval in EU; drug treats patients who don’t require supplemental oxygen but are at increased risk to develop severe disease

AstraZeneca reports EU advisory committee recommends its injectable Evusheld tixagevimab/cilgavimab antibody therapy for approval; treatment aimed at non-hospitalized COVID-19 patients who have increased risk for developing severe disease

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