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AstraZeneca and Ionis' Wainua eplontersen granted first-ever regulatory approval in the US for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis

La Roche licenses Alzheimer's and Huntington's disease drugs from Ionis Pharma in a deal that gives Roche exclusive worldwide rights to the RNA-targeting medicines; Ionis stands to receive US$60M upfront payment, milestone payments and tiered royalties

Ionis pHARMA expands eplontersen agreement with AstraZeneca to include exclusive rights in Latin America; eplontersen is an investigational injectable antisense medicine to treat transthyretin amyloidosis

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