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Roche and Alnylam present positive results from the Phase II KARDIA-2 study of zilebesiran added to standard of care antihypertensives in patients with inadequately controlled hypertension

Roche and Alnylam report successful Phase 2 trial of zilebesiran, showing significant blood pressure reductions in treated adults with mild to moderate uncontrolled hypertension; the study supports potential for twice-yearly dosing

Alnylam presents positive results from the KARDIA-1 Phase 2 dose-ranging study of zilebesiran, an investigational RNAi therapeutic in development for the treatment of hypertension in patients at high cardiovascular risk

Roche and Alnylam's Zilebesiran injectable meets primary and key secondary endpoints in Phase 2 KARDIA-1 study, demonstrating significant blood pressure reduction in adults with hypertension; full results to be presented at upcoming scientific conference

Alnylam Pharmaceuticals plans to appeal Delaware Court ruling on patent dispute with Moderna; Alnylam's separate patent infringement contentions against Pfizer unaffected by this ruling

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