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J&J seeks FDA approval for Tremfya guselkumab to treat adults with moderate to severe active ulcerative colitis, UK approves Daiichi Sankyo’s oral acute myeloid leukemia drug Vanflyta; UK also approves Pfizer’s Velsipity etrasimod

Daiichi Sankyo to invest US$1.08B to expand its production and development site in Pfaffenhofen, Germany, to enhance its capabilities in the antibody-drug conjugate field; the project is expected to create 350 jobs by 2030

FDA grants priority review to AstraZeneca and Daiichi Sankyo's sBLA for Enhertu; drug could be the first HER2-directed treatment and antibody drug conjugate to treat adult patients with unresectable or metastatic HER2-positive solid tumors

Daiichi Sankyo raises sales forecast for AstraZeneca-partnered Enhertu to US$2.6B due to positive developments outside the US, despite lowering the drug's sales estimate in the US to US$1.58B

AstraZeneca and Daiichi Sankyo announce priority review status in the US for Enhertu, a treatment for adults with certain solid tumors without other satisfactory treatment options; product is a jointly developed antibody drug conjugate

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