Cigarette smokers who quit before age 35 years have mortality rates similar to those who never smoked, according to CDC report

Michelle Rivera

WASHINGTON , November 30, 2011 (press release) – Quitting smoking is beneficial to health at any age, and cigarette smokers who quit before age 35 years have mortality rates similar to those who never smoked (1,2). From 1965 to 2010, the prevalence of cigarette smoking among adults in the United States decreased from 42.4% to 19-3%, in part because of an increase in the number who quit smoking (3). Since 2002, the number of former U.S. smokers has exceeded the number of current smokers (4). Mass media campaigns, increases in the prices of tobacco products, and smoke-free policies have been shown to increase smoking cessation (5,6). In addition, brief cessation advice by health-care providers; individual, group, and telephone counseling; and cessation medications are effective cessation treatments (5). To determine the prevalence of 1) current interest in quitting smoking, 2) successful recent smoking cessation, 3) recent use of cessation treatments, and 4) trends in quit attempts over a 10-year period, CDC analyzed data from the 2001-2010 National Health Interview Surveys (NHIS). This report summarizes the results of that analysis, which found that, in 2010, 68.8% of adult smokers wanted to stop smoking, 52.4% had made a quit attempt in the past year, 6.2% had recently quit, 48.3% had been advised by a health professional to quit, and 31.7% had used counseling and/or medications when they tried to quit. The prevalence of quit attempts increased during 2001-2010 among smokers aged 25-64 years, but not among other age groups. Health -care providers should identify smokers and offer them brief cessation advice at each visit; counseling and medication should be offered to patients willing to make a quit attempt.

The 2010 NHIS, which used household-based sampling, interviewed 27,157 persons aged >18 years from the noninstitutionalized, U.S. civilian population; 190 persons were excluded from the analysis for this report because of unknown smoking status. The overall response rate for the 2010 NHIS adult core questionnaire, which included questions on cigarette smoking and cessation, was 60.8%; response rates for the 2001-2009 NHIS survey years have been reported previously.* To determine smoking status, respondents were asked, "Have you smoked at least 100 cigarettes in your entire life?" Those who answered "yes" were asked, "Do you now smoke cigarettes every day, some days, or not at all?" Current smokers were those who had smoked at least 100 cigarettes during their lifetime and, at the time of the interview, reported smoking every day or some days. Former smokers were those who reported smoking at least 100 cigarettes during their lifetime but currently did not smoke. Definitions for attempts to quit smoking and recent smoking cessation were consistent with Healthy People 2020 objectives. ^ Those attempting to quit included 1) current smokers who reported stopping smoking for>l day during the 12 months before the interview because they were trying to quit smoking and 2) former smokers who had quit in the past year. Persons with recent smoking cessation included former smokers who quit in the past year and who had not smoked for >6 months before the interview; the denominator used for prevalences was current smokers who smoked for at least 2 years and former smokers who quit in the past year.

In 2010, NHIS respondents also were administered a supplemental questionnaire that focused on cancer and its risk factors and contained questions on interest in quitting smoking, receipt of a health professional's advice to quit, and use of cessation counseling and medication. Interest among current smokers in quitting smoking was determined by a "yes" response to the question, "Would you like to completely stop smoking cigarettes?" Current smokers and those who had quit in the past year were asked whether they had received medical advice to quit smoking (or quit using other tobacco products) if they had seen a health professional in the past year. Separate questions were asked to assess use of cessation counseling (i.e., one-on-one counseling; a stop smoking clinic, class, or support group; or a telephone help line or quitline) and cessation medications (i.e., nicotine patch, nicotine gum or lozenge, nicotine-containing nasal spray or inhaler, varenicline [U.S. trade name Chantix] or bupropion [including trade names Zyban and Wellbutrin]). Responses to these questions were used to assess treatments used in the past 12 months by current smokers who had tried to quit in the past year and treatments used when they stopped smoking by former smokers who had quit in the past 2 years. All data were adjusted for nonresponse and weighted to provide national estimates; 95% confidence intervals were calculated using statistical analysis software to account for the survey's multistage probability sample design. Logistic regression was used to analyze temporal changes in quit attempts by age group during 2001-2010. These 10-year linear trend analyses were constructed using 200 1 prevalences as the baseline, adjusted for sex and race/ethnicity. The WaId test was used to determine statistical significance (defined as p<0.05). Data also were tested for quadratic trends, which indicated a statistically significant but nonlinear trend in the data over time.

Overall, 68.8% of current smokers indicated they wanted to stop smoking completely (Table 1). Interest in quitting smoking was lower among those aged >65 years (53.8%) than among those aged <65 years (70.2%). By race/ ethnicity, interest in quitting was highest among non-Hispanic black smokers (75.6%), followed by non-Hispanic whites (69.1%), persons of other race/ethnicities (62.5%), and Hispanics (61.0%). A lower proportion of those with education ending at high school graduation reported an interest in quitting (65.9%) than those with some college (73.4%). In addition, those with Medicare (60.7%) or a military health plan (55.3%) were less likely to say they were interested in quitting than those with private insurance (70.4%) or Medicaid (71.2%).

Among current and former smokers, 52.4% had made a quit attempt for >1 day in the year before the interview (Table 1). Quit attempts decreased with increasing age; 62.4% of those aged 18-24 years reported a quit attempt, compared with 43-5% of those aged >65 years. Among smokers aged 45-64 years, a significant linear increase in quit attempts was observed from 2001 to 2010 (p<0.05 for linear trend) (Figure). During that period, the prevalence of quit attempts remained stable among smokers aged 18-24 years and >65 years. A quadratic relationship was observed for quit attempts among those aged 25-44 years, with the peak prevalence of attempts observed in 2010 (56.9%) (p<0.05 for quadratic trend). Quit attempts were more prevalent among non-Hispanic blacks (59.1%) than non-Hispanic whites (50.7%) (Table 1). Persons with <12 years of education (no high school diploma) (46.2%) or those with a high school diploma (46.9%) were less likely to make a quit attempt than those with some college (55.9%) or an undergraduate degree (56.0%).

The overall prevalence of recent cessation was 6.2% (Table 1). Cessation was more likely among non-Hispanic whites (6.0%) than among non-Hispanic blacks (3.3%). Cessation increased with level of education; 3.2% of those with <12 years of education quit smoking, compared with 1 1 .4% of those with an undergraduate degree and 8.1% of those with an associate degree. Those with private health plans (7-8%) were more likely to have quit smoking than those with Medicaid (4.6%) or no health plan (3.6%).

Less than half of smokers (48.3%) who saw a health professional in the past year reported receiving advice to quit (Table 2) . Among those who had visited a health-care provider, women (51.7%) and persons aged >65 years (57-1%) were more likely to have received cessation advice. Hispanic smokers were less likely (34.7%) to have received advice to quit than other racial/ethnic populations. Those without a health plan (35.3%) were least likely to have received cessation advice, whereas Medicare enrollees (59.0.%) were the most likely to receive advice.

Overall, among current smokers who tried to quit in the past year and former smokers who successfully quit in the past 2 years, use of counseling and/or cessation medications was 31-7% (Table 2); 4.3% had used both. Among those who had used counseling and/or cessation medications, 30.0% had used medications (nicotine patch: 14.6%, varenicline: 1 1 .2%, nicotine gum or lozenge: 8.9%, bupropion: 3.2%, and nicotine spray/inhaler: 1.0%), and 5.9% had used counseling (telephone quitline: 3.1%, one-on-one counseling: 2.6%, and stop smoking clinic, class, or support group: 2.4%). Use of counseling and/or medication was higher among women (35.1%) than men (28.8%) and tended to increase with age (18-24 years: 15.8%, 25-44 years: 29.4%, 45-64 years: 42.3%, and >65 years: 35.9%). Non-Hispanic whites (36.1%) were more likely to use counseling and/or medications than non-Hispanic blacks (21.6%) or Hispanics (15-9%). Persons without a health plan (21.5%) were less likely to use counseling and/or medications than those with a health plan (35.6%).

Editorial Note

The findings in this report indicate that, in 2010, 68.8% of current cigarette smokers said they would like to completely stop smoking, and 52.4% had tried to quit smoking in the past year. However, 68.3% of the smokers who tried to quit did so without using evidence-based cessation counseling or medications, and only 48.3% of those who had visited a health-care provider in the past year reported receiving advice to quit smoking. Little overall change has been observed in these measures in the past decade (7,8). However, the prevalence of quit attempts did increase from 2001 to 2010 among those aged 25-64 years. The prevalence of receiving advice from a health professional to quit was lower in 2010 than in 2005, which might have resulted from a change in the NHIS cancer control supplement questionnaire (i.e., a preceding question about whether a health professional asked the participant about tobacco use was removed) (¿?). Advice from a health professional increases quit attempts and increases use of effective medications which can nearly double to triple rates of successful cessation (5).

Cigarette smoking and exposure to secondhand smoke result in approximately 443,000 premature deaths and $193 billion in health-care costs and productivity losses in the United States each year (9). Most smokers establish a regular pattern of smoking and find quitting difficult because they are addicted to nicotine (W). Tobacco dependence is a chronic condition, with many smokers making repeated quit attempts before they achieve long-term success (5). Health-care providers can draw on a number of evidence-based treatment options to assist smokers in quitting. The 2008 update to the Public Health Service Clinical Practice Guideline on Treating Tobacco Use and Dependence concludes that counseling and medication are each effective alone in increasing the prevalence of smoking cessation and are even more effective when used together (5). Individual, group, and telephone counseling are effective in helping smokers quit, and the seven Food and Drug Administration (FDA)-approved first-line cessation medications reliably increase long-term smoking abstinence rates (5). This analysis found that use of medications for cessation was approximately five times more common than use of counseling, which might be influenced, in part, by the widespread availability of over-the-counter cessation medications (e.g., nicotine patch, gum, and lozenge).

The findings in this analysis also observed that, whereas nonHispanic blacks had higher prevalences of interest in quitting and past-year quit attempts than non-Hispanic whites, they had a lower prevalence of recent smoking cessation. Possible contributors to this disparity include non-Hispanic blacks' lower utilization of evidence-based cessation treatments and their high rates of menthol cigarette use (76.7%, compared with 23.6% for non-Hispanic whites [CDC, unpublished data, 20 1 0] ) . The Tobacco Product Scientific Advisory Committee to FDA§ recently concluded that it is more likely than not that the availability of menthol cigarettes results in lower likelihood of smoking cessation success among blacks, compared with smoking nonmenthol cigarettes.

To help smokers and other tobacco users quit, all states now have a cessation quitline that can be accessed through a national toll-free number (1-800-QUIT NOW). Quitlines also can be a referral source for health-care providers who might not have the time or staff to provide all of the steps in the recommended "5A" cessation counseling model: ask about tobacco use, advise to quit, assess willingness to make a quit attempt, assist in quit attempt, and arrange follow-up (5). Quitlines are an effective cessation tool with diverse populations (5) . Reports have shown that certain minority populations attempt to quit as often as or more often than white smokers, but use counseling and medications less often and have lower success rates (5). E-health, Internet, and text-messaging cessation interventions could offer additional potential channels for delivering cessation assistance, considering their accessibility, potential reach, and low cost (5,6). Although more research is needed to establish the effectiveness of these strategies, they likely would appeal especially to young adults, who in this report were the most likely of all age groups to make quit attempts but the least likely to use cessation counseling and medications.

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